Smooth muscle fibers can sustain a contraction without fatigue by allowing dephosphorylated myosin to remain attached to actin in what is called the <u>Latch State</u>.
Latch State- Myosin cross-bridge creation with actin is prevented by dephosphorylating its RLCs, however dephosphorylating myosin that is already attached to actin slows down its off rate, creating the so-called "latch state." In the latch state, smooth muscle maintains tension while undergoing modest rates of ATP hydrolysis.
ATP hydrolysis- When the high-energy phosphoanhydride bonds in adenosine triphosphate are split, as occurs, for example, in muscles, chemical energy that has been stored in them is released. This process is known as ATP hydrolysis.
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Mitosis is one of the precious processes. If it goes wrong then the results will be terrible as it can even bring death to the organism or uncontrollable mutation.
Mitosis is the process in which a cell replicates itself to produce a copy of it. As a result of mitosis, each cell carries the copies of the original cell’s DNA.
The uncertain error in mitosis will cause a mutation which affect the amino acid sequence and further functions. This will lead to the cell cycle disruption that can lead to the formation of cancer cells that are uncontrollable in dividing itself.
The main functions of mitosis are growth and repair. Some cells once fully formed do not undergo cell division, such as nerve cells and muscle cells. Since you can never re-grow or repair these types of cells once they are mature, you must take care of the ones you have.
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