Question

JC has systolic heart failure with an ejection fraction of 33%. Which of the following medications could possibly worsen JC's heart failure?
A) Itraconazole
B) Verapamil
C) Prednisone

Answer 1

Answer:

The correct answer is - option A, B, C.

Explanation:

Itraconazole is a antifungal medication that is prescribed to treat infection occur due to fungus. It is considered as potentially dangerous as the side effects on the heart of a heart patient due to its ability to decrease cardiac contractility. Itraconazole including congestive heart failure (CHF) as one of the side effect on the heart .

Verapamil used to treat the angina, heart rhythm by relaxing that heart which can damage, heart, the blood vessels of the brain and kidneys, leads to the heart failure, or stroke.

Prednisone is a medication that is used as an immunosuppressant or an anti-inflammatory medication, it can worsen the heart condition by suppressing the immune response.

Thus, the correct answer is - option A, B, C.

Answer 2

Answer:

All options are correct.

Explanation:

Systolic heart failure is the common heart failure and the pumping of the blood in the body is not effective, The main symptoms associated with the heart failure are chest pain and the irregular heart beat.

The drugs like verampil, prednisone and traconazole might worse the heart failure and should be avoided by the patient. These drugs are against the actions of the diuretics and shows the negative ionotropic effect. This causes the increase of the cardiac work load and increase in cardiotoxicity.

Thus, all given options are correct.