Because in order to do anything that's fun, like hanging out with friends,
learning math, going to the beach, reading a book, playing with a dog,
going for a bike ride, going to school, and like a whole bunch of other
things like those, you like have to be living, or else like none of it works.
1. if the person is saying goodbye to everyone and saying sorry and how much they love them
2. if they write a note
3. when the person starts giving up on everything
4. if the person is drowning in self pity they tend to think suicidal
5. signs of being depressed or emotional outburst for no reason
Answer:
Multiple sclerosis (MS) is the most common demyelinating and an autoimmune disease of the central nervous system characterized by immune-mediated myelin and axonal damage, and chronic axonal loss attributable to the absence of myelin sheaths. T cell subsets (Th1, Th2, Th17, CD8+, NKT, CD4+CD25+ T regulatory cells) and B cells are involved in this disorder, thus new MS therapies seek damage prevention by resetting multiple components of the immune system. The currently approved therapies are immunoregulatory and reduce the number and rate of lesion formation but are only partially effective. This review summarizes current understanding of the processes at issue: myelination, demyelination and remyelination—with emphasis upon myelin composition/architecture and oligodendrocyte maturation and differentiation. The translational options target oligodendrocyte protection and myelin repair in animal models and assess their relevance in human. Remyelination may be enhanced by signals that promote myelin formation and repair. The crucial question of why remyelination fails is approached is several ways by examining the role in remyelination of available MS medications and avenues being actively pursued to promote remyelination including: (i) cytokine-based immune-intervention (targeting calpain inhibition), (ii) antigen-based immunomodulation (targeting glycolipid-reactive iNKT cells and sphingoid mediated inflammation) and (iii) recombinant monoclonal antibodies-induced remyelination.Keywords: calpain, central nervous system, demyelination, fingolimod, glycolipids, lipids, multiple sclerosis, myelin, myelination, NKT cells, oligodendrocytes, remyelination, T cells
Explanation:
Answer:
you could learn to live happier,healthier understand the human mind a lot better and how it works you could be saving your life and saving others from sadness if you do have sucidial thoughts if you get mental help it could make you understand why thou have your thoughts and how to train them
