Question

What would happen if a replicated chromosome failed to correctly attach to the mitotic spindle?

Answer 1

Answer:

The chromosomes will not be separated and the cell cycle will be blocked

Explanation:

Chromosome separation is one of the key steps during the formation of daughter cells during M-phase.

The chromosome segregation is proceeded by the attachment of the mitotic spindle (cytoskeletal structures) to the kinetochores of the chromosomes during metaphase.

If the chromosomes are not attached to the mitotic spindles or the kinetochore not properly attached to the spindle than a cell cycle checkpoint called spindle assembly checkpoint will not allow the cell to enter anaphase and the cell cycle will not proceed.

Thus, the chromosomes will not be separated and the cell cycle will be blocked is correct.