Stimulants are substances that all result in the increase of levels of dopamine in the brain, which is a neurotransmitter that affects attention and pleasure. What this means is that stimulants affect our brain and the way it works by changing the ways that nerve cells communicate.
Neurons (nerve cells) are the cells that have a role in transmitting messages from the brain to other parts of our body, and vice-versa, which is important for pain response, alertness, energy etc.
With long-term use, the use of stimulants would affect the central nervous system (speeding it up), the brain, and the functions necessary to live, like respiration, heart rate, blood pressure, body temperature. Levels of neurotransmitters like dopamine, serotonin, and GABA, which are responsible for the regulation of different processes, are also impacted, which creates a chemical disbalance ultimately resulting in behavioral changes, mood swings, altered attention, movement and energy, stress etc.
So the part of the body that is affected the most with the long-term use of stimulants like cocaine, nicotine, methamphetamine is the brain of course, which is where these substances have the most impact, but the impact on the central nervous system, autonomous nervous system, and neurotransmitter levels is significant.
Explanation: Ribosomes are manufactured in the nucleolus. Ribosomes are the sites where protein synthesis takes place. Ribosomes are usually made up of two subunits: one large subunit and one small subunit. Ribosomes are manufactured and assembled in the nucleolus. Ribosomal proteins combines with four ribosomal RNA strands in the nucleolus to form two ribosomal subunits: one small subunit and one large subunit that make up the complete ribosome
Modern stromatolites – living fossils. Originating over 3 billion years ago, stromatolites are the oldest known fossils (timeline). Fossilized stromatolites were laid down as colonial structures built by photosynthesizing Cyanobacteria and other microbes.
Daedalus, (Greek: “Skillfully Wrought”) mythical Greek inventor, architect, and sculptor who was said to have built, among other things, the paradigmatic Labyrinth for King Minos of Crete. Icarus and Daedalus, etching by Giovanni David, 1775; in the Metropolitan Museum of Art, New York City.
