What happened is jealousy can ruin a family and everything,a brother was jealous of his own brother because he was powerful,caring and every body loved him, so he tried to do anything to kill him, and he lied to him and told him your son is in trouble and it end up having him killed and he told everybody his son killed him.
Allosteric regulation occurs at these points where the concentration of the substrate and/or products is important for the activation and inhibition of the enzyme.
