Well I can speak from experience when I went to my midlife crisis I was basically focusing on my career at which point there was confusing for me it wasn't clear as to what I want to do.
Answer:
Major Depressive Disorder
Explanation:
Major depressive disorder, also known as depression, is a mental disorder that is characterized by symptoms of discouragement, sadness, unwillingness, fatigue, easy crying, lack of pleasure, difficulty concentrating, changes in appetite, insomnia, loss of libido, among other manifestations. People with major depressive disorder have depressed mood most of the time, almost daily, with a feeling of emptiness, sadness, and hopelessness. Jorge has many symptoms related to major depressive disorder, so we can say that she may be suffering from major depressive disorder.
All are possible physical changes