Answer:
(a) 1/2; (b) no
Explanation:
Glucose-6-phosphate dehydrogenase deficiency (G6PD) is an X-linked recessive disorder and the woman's father was diseased so it means that woman is a carrier of the allele but has normal phenotype. It means that she will have XXᵇ genotype.
In contrast to this, her husband is diseased so his genotype will be XᵇY.
The Punnett square diagram related to the cross is attached.
(a) Proportion of their sons expected to be G6PD is 1/2:
They both may give birth to 4 progeny with genotypes XXᵇ, XᵇXᵇ, XY and XᵇY. It means they both may have 2 sons out of which one with genotype XᵇY will be diseased while the one with genotype XY will be healthy. So the proportion of their sons having G6PD is 1/2 or 50%.
(b) If the husband were G6PD deficient, the answer will not change.
The reason behind this is that this disease is caused by an allele located in X chromosome. But father contributes only Y chromosome to his son not X chromosome. The X chromosome will affect the genotype of his daughter not son that is why answer will not change. It means they will still have 1/2 of their sons diseased.
Answer:
The plasma membrane is made up by a phospholipid bilayer with embedded proteins that separates the internal contents of the cell from its surrounding environment. Only relatively small, non- polar materials can easily move through the lipid bilayer of the plasma membrane.
Explanation:
Cytokinesis is the part of the cell division process during which the cytoplasm of a single eukaryotic cell divides into two daughter cells.
Answer:
The effect of amanitin on the maximum elongation rate for the wild-type and modified RNA polymerases is that it binds to the RNA polymerases, and reduces the process of translocation which is essential for RNA synthesis that is required for RNA polymerases elongation.
Explanation:
Amanitin is a peptide that is cyclic in nature. It is repelled by water thereby making it an hydrophobic peptide.
Amanitin is a toxic peptide that is found in Amanita ( a type of mushroom).
Alpha Amanitin in particular is the one that affects the elongation rate of RNA Polymerases in the body.
When Alpha Amanitin gets into the body system, it travels straight to the liver and due to its very strong affinity for RNA polymerases, it immediately attaches itself to them.
After the attachment, Alpha Amanitin, is disturbs the bridge helix found in RNA polymerase, preventing the hindering and slowing down the proces of translocation from happening.
Once translocation is hindered, RNA is no longer synthesized. Hence, the elongation of RNA polymerases is hindered and this results in severe illness in the body such as liver failure, cytolysis of the liver
