A high-energy electron is transferred along an electron transport chain to the inner mitochondrial membrane. Hydrogen is pumped out of the matrix space by the energy released. Through ATP synthase, the gradient produced by this forces hydrogen back through the membrane. when participating in the crucial process of oxidative phosphorylation.
Only a tiny portion of the glucose's totally free energy is released when it is transformed into pyruvate by the glycolytic process.
The breakdown of glucose into pyruvate within a cell's cytoplasm is known as glycolysis. The final phase of cellular respiration, known as oxidative phosphorylation, generates ATP using an ATP synthase gradient and a hydrogen ion gradient. The majority of the ATP produced during cellular respiration is produced during this process. Pyruvate can diffuse into mitochondria under aerobic conditions, where it enters the citric acid cycle and has reducing equivalents in the forms of NADH and FADH2.
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