If you go on mc3.edu/admissions/applying-to-mccc/testing-and-assessment/assets/biology-placement-test.pdf page 11 it will tell you all the answers to your questions....
C Chromosomes break at centromeres,and sister chromatids move to opposite ends of the cell.
Amino acid differs at the glutamine, which is converted to valine in hemoglobin S. the body produced hemoglobin S due to a point mutation in the DNA sequence which results in different amino acid to be formed during translation of DNA sequence codons.
A base substitution of G:C to A:T after two rounds of replication.
