During the pentose phosphate pathway, glucose 6-phosphate is first converted into 6-phosphoglucono-lactone in the reaction catalyzed by glucose 6-phosphate dehydrogenase. The 6-phosphoglucono-lactone is then converted into 6-phospho-gluconate which in turn undergoes decarboxylation to form D-ribulose 5-phosphate and the C-1 of original glucose 6-phosphate is released in form of CO2.
Therefore, to observe the most rapid production of labeled carbon atom in form of CO2, the C-1 of glucose should be labeled.
Relation between mutagens and carcinogens. Mutagenicity and carcinogenicity are clearly correlated. One study showed that 157 of 175 known carcinogens (approximately 90 percent) are also mutagens. The somatic mutation theory of cancer holds that these agents cause cancer by inducing the mutation of somatic cells.
These are normal symptoms, since the uterus where the baby lies is pushing up on the diaphragm which may cause shortness of breath. This client does not need to be seen as discomfort is common especially considering how far along she is.
