In order to create an exosomes miRNA panel for predicting recurrence after surgery in patients with PDAC, we undertook genome-wide expression profiling.
Offering patients with pancreatic ductal adenocarcinoma (PDAC) personalized therapy requires pre-treatment risk classification, yet it is still difficult to predict recurrence after surgery. plasma and serum samples from four cohorts of PDAC patients were examined. We carried out genome-wide sequencing on a discovery cohort (n = ) to find potential exosomes miRNAs (exo-miRNAs). Then, using two clinical cohorts without neoadjuvant therapy (NAT) (training cohort: validation cohort: ) and a post-NAT clinical cohort (n =, we trained and validated the exo-miRNAs' predictive performance.
Learn more about surgery in patients with PDAC here.
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Energy can move to something else or another part of something-transfer.
Conduction is an example.
Energy transformation is one energy form changing to another kind of energy.
Chemical energy is transformed into mechanicle energy in a car.
Just learned this in school