Disruption of axonal transport would be a good target for his drug.
<h3>What is disruption of axonal transport?</h3>
- Axonal transport defects are among the early molecular events leading to neurodegeneration in mouse models of amyotrophic lateral sclerosis (ALS).
- Gene expression profiles indicate that dynactin-1 mRNA is downregulated in degenerating spinal motor neurons of autopsied patients with sporadic ALS.
- Disruption of axonal transport also underlies the pathogenesis of spinal muscular atrophy and hereditary spastic paraplegias.
- The neurotoxin β,β′-iminodipropionitrile (IDPN) selectively disrupts slow axonal transport without affecting fast anterograde or retrograde axonal transport.
- Impairment of slow axonal transport causes a proximal accumulation of neurofilaments.
- Because neurofilaments regulate axonal diameter, this accumulation leads to a marked swelling of the axon.
- Acrylamide causes decreased axonal transport, also causing proximal accumulations of neurofilaments and swelling.
To learn more about axonal transport,
brainly.com/question/10600853
#SPJ4
Explanation:
Muscle tissue is metabolically more dynamic and burn a larger number of calories than fat tissue. The more muscles you have, the greater your resting energy expenditure, which implies that your body burns more calories while sitting idle
Answer:
lichen
Explanation:
Common examples of pioneer species include bacteria, lichen, mosses, and fungi.
Answer:
(08) and (32)
Explanation:
To make osmosis happen there has to be a difference in the concentration of solutes, between the inside and the outside of the cell. To valance this difference in concentration, water has to flow towards a place that has a higher number of solutes.
The lipids in the cell's wall make this membrane semipermeable. This allows the passage of specific components only, such as water through aquaporins. Lipids and other elements are of importance in the barrier because they maintain the cell separated from the outside, allowing it to be balanced as regards the different substances that can interact with it.
The statements that describe steps taking place in the nitrogen cycle are
- Many biotic and abiotic factors play a role in recycling nitrogen ( A )
- Farming practices and chemicals lead to a build-up of nitrates in the soil ( E )
Nitrogen cycle is biochemical process whereby nitrogen is converted to various chemical forms as it passes through the atmosphere, Marine and terrestrial ecosystems .
Nitrogen cycle undergoes four ( 4 ) important processes which are :
- Fixation
- Ammonification
- Nitrification and
- Denitrification
Hence we can conclude that The statements that describe steps taking place in the nitrogen cycle are :
Many biotic and abiotic factors play a role in recycling nitrogen and
Farming practices and chemicals lead to a build-up of nitrates in the soil
Learn more about Nitrogen cycle : brainly.com/question/1380063
