1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
mash [69]
3 years ago
9

How does cell proliferation affect the symptoms and the course of Zollinger-Ellison syndrome?

Medicine
1 answer:
Jobisdone [24]3 years ago
4 0

Answer:

ascular endothelial cells are an established source of thrombospondin 1 (TSP1), a multifunctional extracellular matrix molecule. TSP1 appears to play an important role in modulating endothelial cell functions such as proliferation, migration, and capillary morphogenesis. In addition, TSP1 has recently been reported to potently inhibit angiogenesis both in vitro and in vivo. To better understand the mechanism underlying the antiangiogenic property of TSP1, endogenous TSP1 production was disrupted in bovine aortic endothelial cells (BAEC) by stable transfection with a vector expressing a TSP1 antisense RNA. Stable transfectants in which the antisense vector caused a decrease in TSP1 production were assayed for their ability to form capillary-like cords on gelled basement membrane matrix and for their responsiveness to the angiogenic/chemotactic mediator basic fibroblast growth factor. BAEC in which TSP1 production was disrupted exhibited a ten-fold increase over control BAEC in chemotactic activity to basic fibroblast growth factor and a twofold increase over control cells in the number of capillary-like cords that formed on gelled basement membrane matrix. Thus, the down-regulation of endogenous TSP1 appears to facilitate endothelial cell chemotaxis and capillary morphogenesis. These studies suggest that the modulation of TSP1 production is an important component of the angiogenic response, and support the idea that soluble TSP1 inhibits angiogenesis by interfering with endothelial cell chemotaxis and capillary formation.

Explanation:

 .

You might be interested in
What's the most common use of computers in the pharmacy ?
hammer [34]
A. Hhdhhjfjfjjfjfjjf
8 0
3 years ago
_______ is classified as a Schedule-III controlled substance.
Morgarella [4.7K]

Answer:

Testosterone

Explanation:

Testosterone (including all anabolic steroids) are schedule III according to DEA.

8 0
2 years ago
Choose all correct answer
Digiron [165]

Answer:

I think viruses, bacteria,fungi and parasites.

8 0
2 years ago
Read 2 more answers
Which among the following defines GPI anchored proteins
Tanya [424]

Answer:

Glycosylphosphatidylinositol (About this soundpronunciation (help·info)), or glycophosphatidylinositol, or GPI in short, is a phosphoglyceride that can be attached to the C-terminus of a protein during posttranslational modification.

4 0
2 years ago
Osteoporosis is a bone disease caused by loss of bone density. What type of bone
KatRina [158]
C. Mostly the spongy and also the compact
3 0
2 years ago
Other questions:
  • The vocal folds open when we breathe in & vibrate against each other as air exits from the lungs & through the _________
    12·1 answer
  • What function is most directly lost when helper T-cells die?
    8·1 answer
  • Cortisol and epinephrine are first released in this stage
    15·1 answer
  • Zoom in to 400x on the onion root tip. You should be able to see square-like shapes with dark areas in the center. Based on what
    11·1 answer
  • How can you tell when a sentence in a play is left incomplete?
    13·2 answers
  • Front of the body
    7·1 answer
  • Please send help! I’ll take the answer key or anything!!
    5·1 answer
  • Imagine an athlete the day after sustaining a head injury sitting in class suffering the symptoms of a concussion (e.g., slurrin
    15·1 answer
  • Switching drugs to otc status generally increases costs for insured patients.
    13·2 answers
  • A/an ____________________ is the partial or complete suturing together of the upper and lower eyelids.
    10·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!