<em>1. </em><span><em> the theory that Earth's outer shell is divided into several </em></span><em>plates</em><span><em> that glide over the mantle</em>
<em>2. I am not sure</em>
<em>3. </em></span><span><em>Earth's mantle contained convection cells that dissipated radioactive heat and moved the crust at the surface</em>
<em>4. </em></span><span><em> supercontinent that existed during the late Paleozoic and early Mesozoic eras.</em>
<em>5. </em></span><span><em> the </em></span><em>theory</em><span><em> that the outer rigid layer of the earth (the lithosphere) is divided into a couple of dozen "</em></span><em>plates</em><span><em>" that move around across the earth's surface relative to each other, like slabs of ice on a lake.</em>
<em>6. </em></span><span><em>Africa and South America.</em>
<em>7. I am not sure</em>
<em>8. </em></span><span><em>a small area or region with a relatively hot temperature in comparison to its surroundings.</em>
<em>9. </em></span><em>As the plate moves over a fixed spot deeper in the Earth where magma (molten lava) forms, a new volcano can punch through this plate and create an island. </em>The Hawaiian Islands are believed to be formed from one such 'hot spot'.
Answer:
Option D, both A and B
Explanation:
The potential difference is created across a battery (between its two terminal –one positive and the other one negative) when work is done to move a charge from one point to another. This potential difference is measured in volts. 1 volt is the potential difference between two points when one joule of potential energy is spent to move a charge of one coulomb from one point to the other.
Voltage drop across a circuit is the amount of electric current lost due to resistance/ impedance with in the cables of the circuit.
Hence, both potential difference and voltage drop occurs across the circuit,
Option D is correct.
M1V1=M2V2
M1 * (650 ml) = 0.675 M *450 ml
M1= (0.675 M * 450 ml) / 650 ml
M1= 0.467 M
Answer:
1. P120 is degraded in the 26S proteasome
2. The 26S proteasome has a major role in protein degradation and is critical for protein homeostasis
3. Cell cycle and DNA replication are cellular processes regulated by the Ras and NFkB pathways
Explanation:
The proliferation-associated nucleolar protein (p120) is a protein known to be expressed during the interphase of the cell cycle, specifically in G1 and early S phase, where any problem with DNA replication trigger a checkpoint, i.e., a molecular cascade of signaling events that suspend DNA replication until the problem is resolved. In mammalian cells, the 26S proteasome is responsible for catalyzing protein degradation of about 80% (or even more) of their proteins. The 26S proteasome acts to degrade rapidly misfolded and regulatory proteins involved in the cell cycle, thereby having a major role in protein homeostasis and in the control of cellular processes. It is for that reason that inhibitors that block 26S proteasome function have shown to be useful as therapeutic agents in diseases associated with the failure of protein degradation mechanisms (e.g., multiple myeloma). The NF-κB are highly conserved transcription factors capable of regulating different cellular processes including, among others, cellular growth, inflammatory responses and apoptosis. Moreover, the MAPK/ERK pathway is able to transduce different signals received on the cell surface to the nucleus. The MAPK/ERK pathway is activated when a singling molecule binds to a cell receptor which triggers a signaling cascade that ends when a transcription factor induces the expression of target genes, ultimately producing a response in the cell (for example, the progression through the cell cycle).
This produces medicines that can possibly save the lives of cancer infected patients who otherwise could die.
