Answer:
I believe c not completely sur e though
Explanation:
 
        
                    
             
        
        
        
To have an overall positive or negative charge. (as opposed to neutral one)
        
                    
             
        
        
        
D.)The enzyme changes shape and no longer fits the substrate.
High temp causes enzymes to speed up the reaction but too much heat and the enzyme might denature, losing its shape. 
 
        
             
        
        
        
Answer:
drinking water after a long run
Explanation:
When there arises a change or shift in the state or action of any organism because of any external stimulus, the result is said to be the response to external stimulus. The response or reaction to the external stimulus arises when the organism experiences or senses the stimulus.  
Drinking water after a long run is an example of the response to external stimulus. Here, the external stimulus is the loss of water in the water because of the action of running. This makes the individual drink water which is a response to the external stimulus.