Answer:
Bridgham et al. (2006) showed that the interaction between a steroid hormone (aldosterone-M) and its receptor (mineralocorticoid) evolved by Darwinian gradualism. In this work, the authors demonstrated a primitive affinity between the hormone and its receptor that was initially present in chemically similar but more ancient ligands. This result has implications in understanding the association between gene duplication and the evolution of hormone signaling pathways. For example, in invertebrates, this work reinforces the importance of gene duplication in the existing interaction between paralogous glucocorticoid receptors and their receptor mineralocorticoid genes that were derived from duplication (Thornton 2001).
The publications above cited are the following:
J.T. Bridgham, S.M. Carroll, and J.W. Thornton (2006). Evolution of hormone-receptor complexity by molecular exploitation. Science, 312(5770), 97-101.
JW Thornton. Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions, Proc Natl Acad Sci USA (PNAS), 2001, vol. 98 10 (pg. 5671-5676).
Answer:
The cytosolic and mitochondrial pools of CoA are kept separate, and no radioactive CoA from the cytosolic pool enters the mitochondrion.
Explanation:
- Fatty acyl group condensed with CoA in the cytosol are first transferred to carnitine and in this process, CoA is released.
- After this, it is transported into the mitochondrion, where it is again condensed with CoA.
- In this way, the cytosolic and mitochondrial pools of CoA are kept separate, and due to this reason, no radioactive CoA from the cytosolic pool enters the mitochondrion.
- Therefore, according to the given question, the C14 CoA that is added into the liver homogenate along with palmitate shows cytosolic radioactive fraction but not mitochondrial as in the mitochondria a different CoA joins palmitate and not the one containing C14.
The best way to calm a person when he or she is talking
about painful stress producing experiences is by having his or her activity to
be reduced in which is under the limbic system as this will allow the person to
relax and be calm.
I believe it's totipotent, pluripotent, and multipotent.
Answer:
"The fossil plant Elkinsia polymorpha, a “seed fern” from the Devonian period (about 400 million years ago) is considered the earliest seed plant known to date."
