General anesthesia or general anesthetics can be defined as substances that triggers a loss of consciousness in individuals. These medications show their effect by activating inhibitory CNS and by inactivation of excitatory receptors of CNS.
They target both GABA (gamma-aminobutyric acid) and NMDA (N-methyl-D-aspartate) receptors of CNS. General anesthetics agonist effect with GABA receptors and antagonist effect with NMDA receptors, and induces state of unconsciousness.
Meaningful choices and course of action to keep an individual safe from harm while participation in physical activity is called an Injury Prevention Plan.