Genetics, blood type gene has two alleles, each allele has genotype A, B or O. The A and B are dominant, and O is recessive. So allele A combined with allele O is type A. Similarly, BO is type B, AA is type A, BB is type B, OO is type O, and AB is typeAB.
If both parents have type A blood, then the alleles could be AA or AO, thus the allele A frequency is 75%, allele O frequency is 25% for both parents.
So the chance of alleles OO is 25% × 25% = 6.25%,
alleles AA is 75% × 75% = 56.25%,
alleles AO is 75% × 25% = 18.75%,
alleles OA is 25% × 75% = 18.75%.
Since AA, AO and OA are blood type A, and OO is blood type O, thus their child has 6.25% chance to be blood type O and 93.75% chance to be blood type A.
The +/- is called the rhesus factor, with + being dominant, and - being recessive.
So if both parents are -, the kids are always -, otherwise the kids might be + or -.
Child Blood Type Estimate Table:
Father's Blood TypeABABOMother's
Blood
TypeAA/OA/B/AB/OA/B/ABA/OBA/B/AB/OB/OA/B/ABB/OABA/B/ABA/B/ABA/B/
Answer:
Semi-conservative replication
Explanation:
After the double-helix discovery of Watson and Crick, there were three possible models about the DNI replication:
- The Conservative model stated that the two strands of DNI together were the template of another new molecule. The final product was the original double-stranded molecule and the new molecule.
- The semi-conservative model stated that the original DNI molecule separated into two strands, and each of them served as a template for the synthesis of a new complementary strand. The replication product would be two double-stranded DNA molecules, each carrying an original strand a new one.
- The Dispersive moles stated that the replication product would be two molecules made by a mixture of segments of the original and the new molecules.
Meselson and Stahl joined to discover which of the models was the correct one. To do it they used E. coli and Nitrogen isotopes.
- First, they extracted DNI from bacteria grown in a medium with N¹⁴ and got its density band by centrifugation.
- Then they grew bacteria in a medium with N¹⁵, extracted their DNI molecules, centrifugated them, and got the density band, which was heavier than the firsts ones.
- The researchers then transferred bacteria grown in medium with N¹⁵ to a medium with N¹⁴, and they allowed only one replication process to occur. DNI was extracted and centrifugated again, and a new band appeared. This band was an intermediate form between bands of DNI-N¹⁵ and DNI-N¹⁴.
This event <em>eliminated the conservative model</em>. If this model were correct, the expected result would be to get two bands: one corresponding to the density DNI-N¹⁵ and the other corresponding to the density DNI-N¹⁴.
- Bacteria grown in a medium with N¹⁵ and then transferred to a medium with N¹⁴ were finally allowed to replicate twice. Their DNI was extracted and centrifugated. The result was two bands: one of them coincided with the intermediate band, and the other one with the DNI-N¹⁴.
<u>This result was conclusive</u> because if the dispersal model were correct, these two bands should not appear, as all the DNI strands would have part of the original molecule.
With this experiment, Meselson and Stahl proved that the correct replication model was the semi-conservative one.
Answer:In humans, gametes are haploid cells that contain 23 chromosomes, each of which a one of a chromosome pair that exists in diplod cells.
Explanation:
Answer:
A mutation that causes a single letter change in the DNA sequence can affect your protein structure and function because the sequence of letters in a gene determines the sequence of amino acids in the protein that it encodes. A single letter change in the DNA alters the mRNA which alters the amino acid sequence of the resulting protein and sometimes that can cause serious results if it changes the way a protein works.
