Two-component regulatory systems rely on a balance of phosphorylation and dephosphorylation of sensor kinases and response regul
ators. If the response regulator became permanently phosphorylated due to lack of phosphatase activity, which of the following would NOT happen? Hints O The cell would become more sensitive to the environmental stimulus The cell would become insensitive to the environmental stimulus. The cell would not be able to "reset" its response cycle. O The operon controlled by the response regulator would be always transcribed or never transcribed, depending upon the regulatory role of the response regulator.
A fundamental stimulus-response coupling mechanism that helps various species to react and sense different modifications taking place in various distinct environmental circumstances is known as a two-component regulatory system. Though this system is found in almost all the domains of life, however, it is generally witnessed in species like bacteria, mainly in the Gram-negative and cyanobacteria.
In case, if the response regulator turns completely phosphorylated because of the absence of phosphatase activity, the cell would become insensitive towards the environmental stimulus. This generally happens as the cell will lose its tendency to sustain the response cycle because of the imbalance in the dephosphorylation and phosphorylation system that helps in sustaining the response of the cell towards a specific environmental stimulus.
