In 1637 colonists killed between 500 and 600 American Indians in connecticut during the Pequot War.
Explanation:
The Pequot War was an armed conflict between the Pequot tribe and English settlers that occurred between 1636 and 1638. This tribe, like its neighbors, had been seriously weakened by epidemics of bubonic plague, smallpox and hepatitis A in 1616-1619 and another of smallpox in 1633, losing from 55 to 95% of its population. From 12,000 to 15,000 Indians there were 3,000 to 5,000 survivors. The Pequot lost the war and five hundred to a thousand were killed (only 300 warriors) and 500 were taken prisoner and integrated by the neighboring tribes, other hundreds were sold as slaves in the West Indies. Others were dispersed. The defeated were almost exterminated and it would take them almost three and a half centuries to recover many of their original lands. The Mohegan and the Narragansett would end in 1643 declaring war on each other.
