Answer:
Explanation:
The switch from glutamic acid to valine in position 6 of hemoglobin (HB) forms the basis of sickle cell anemia disease pathology.
Valine is hydrophobic and it's chain is shorter than glutamic acid. The lack of the carboxylic acid and shortness of valine will result in loss of the ionic interactions formed between the glutamic acid's carboxylic group and other amino acids. A hydrophobic cavity will form in the beta sheet of HB due to the short and hydrophobic structure of valine. For these reasons, the HB molecule will be less stable and insoluble in water. The insolubility is thought to be caused by fibril formation between the valine interacting with hydrophobic pocket residues of the adjacent HB molecule. This would in turn affect binding of oxygen to HB.
Answer:
Replicates can be used to measure variation in the experiment so that statistical tests can be applied to evaluate differences. Averaging across replicates increases the precision of gene expression measurements and allows smaller changes to be detected.
Explanation:
Given what we know, we can confirm that the process of differentiation alters the cells by changing the expression of genes in a cell.
<h3>What is differentiation?</h3>
- differentiation is when a cell becomes specialized.
- This is the case with heart or digestive cells.
- Since all cells carry the same DNA, this does not account for differentiation.
- Instead, this is achieved by changing the expression of genes in a cell.
Therefore, we can confirm that differentiation is what we refer to as a cell becoming specialized in one way or function, such is the case with heart cells or digestive cells, and since all cells in the body carry the same DNA, this is done by changing the way in which the cells express their genes in the DNA.
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Answer:
i really dont know but i did try to help u
Explanation:
Answer:
vacuole.
Explanation:
The function of the vacuole is to store fluids for the cell.
