The rules of base pairing explain the phenomenon that whatever the amount of adenine (A) in the DNA of an organism, the amount of thymine (T) is the same (Chargaff's rule). Similarly, whatever the amount of guanine (G), the amount of cytosine (C) is the same.
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Answer:
p53 helps the cells from passing on mutations that lead to DNA damage. Hence, it is known as the guardian angel of the cell as it helps fight against cancer. However, if p53 becomes defective or missing, then the mutations will lead to cancer.
Mutations in the p53 can also cause the tumor-suppressing genes to convert into tumor causing genes. Hence, mutations in such kind of genes can be very harmful for the body.