Drugs interfere with the way neurons send, receive, and process signals via neurotransmitters. Some drugs, such as marijuana and heroin, can activate neurons because their chemical structure mimics that of a natural neurotransmitter in the body.
The most common site are the skin overlying the sacrum, coccyx, heels or the hips, but other site such as the elbows,knees, ankles or the back of the cranium can be affected.
A or b not really sure who would know that not to many people would know
