Answer:
(C) Aminoacyl-tRNA synthetases have an additional active site that binds to non-cognate tRNAs. The tRNAs that bind to this second active are hydrolyzed and released from the enzyme.
Explanation:
In case of translation, proof reading is done by aminoacyl-tRNA synthetases only. Aminoacyl-tRNA synthetases have two mechanisms to avoid error during translation which are mentioned as under:
<u>(1) Chemical proof reading:</u> Incorrect amino acids rather than being hydrolyzed in catalytic pocket get hydrolyzed in editing pocket and thus they hardly get attached to tRNA.
For example: For distinguishing similar amino acids like isoleucine and valine, isoleucyl-tRNA synthetase uses a second active site which is meant for only valine not for isoleucine. In this particular site, valine which had entered the enzyme is cleaved away with the help of editing reaction after which the enzyme is well prepared to process isoleucine which is the correct amino acid for this enzyme.
<u>(2) Kinetic proof reading: </u>Even if an incorrect amino acid has entered a particular aminoacyl-tRNA synthetase, it does not cause appropriate conformational change in the enzyme because of which the incorrect amino acid loosens from the enzyme and does not get incorporated.
Note: In this example, only chemical proof reading is mentioned not kinetic proof reading.
<h3><u>Connective tissue:</u></h3>
It is the layer under the epithelial tissue in the body. It is stronger than epithelial tissue and is found in many organs. It provides protection.
<h3><u>Epithelial tissue:</u></h3>
It covers the outside of the body like a veil. located in the outermost part of the body. Protects the body against microbes and infections.
<h3><u>Muscle tissue:</u></h3>
It is located in the joint areas and forms the support and movement system. It allows us to make bodily movements.
<h3><u>Nervous tissue:</u></h3>
It is the fastest communication tissue. It allows us to feel pain and the sense of touch. It is impossible to repair this tissue after it is damaged. It causes paralysis. It is very important as it plays a role in the activity of neural transmission.
It should be the last one, but if you can pick more than one answer then I would do the first and last one but I’m confident that it would be the last one either way :) hopefully this is helpful
These abnormalities occur in the serotonin system which reduces and/or inhibits control in their movement. This disruption of the neurotransmitter causes them to act maladaptively. Thank you for your question. Please don't hesitate to ask in Brainly your queries.