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Komok [63]
3 years ago
12

Describe the typical principles used to identify topogenic sequences within proteins and how these principles can be used to dev

elop computer algorithms. How does the identification of topogenic sequences lead to prediction of the membrane arrangement of a multipass protein
Biology
1 answer:
Sonja [21]3 years ago
6 0

Answer:

Topogenic sequences share a series of structural features, and thereby computational algorithms can be used to predict these protein-membrane segments  

Explanation:

Topogenic sequences are protein segments formed by alpha-helical transmembrane domains, which are required for the insertion of membrane proteins. These domains share a series of well-defined features: they are composed of segments of about 20 hydrophobic amino-acid residues. In consequence, computational algorithms can be designed to identify protein patterns that fulfill these structural requirements (i.e. segments with a length of 20 residues, hydrophobic level, etc). The models assign a similarity threshold (threshold value) that predict if the similarity level of the protein pattern is good enough to detect a topogenic segment.

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6 0
2 years ago
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dalvyx [7]
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2 years ago
PLS HELP ASAP!!!!!
frozen [14]

Answer:

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Explanation:

For the model of prokaryotic cell, we construct the model by removing organelles from the cell whereas in the eukaryotic cell, we add the organelles because in eukaryotic organisms, organelles are present in the cell that performs specific function. In the model of prokaryotic cell, we have to remove membrane around the nucleus whereas membrane president around the nucleus. In the prokaryotic cell, nucleus is not visible while on the other hand, in eukaryotic cell, the nucleus is visible and can be differentiate from other organelles.

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