Because it is easily accessible and has a mild immune response, the retina makes a good target for gene therapy.
- In a mouse model, the inner retina was highly effectively transduced by an intravitreally injected adeno-associated virus (AAV) vector.
- The vitreous and internal limiting membrane (ILM) operated as obstacles to transduction in large animals, reducing the efficacy of retinal transduction.
- Before administering AAV vectors, we performed vitrectomy (VIT) and ILM peeling on cynomolgus monkeys to get around these obstacles.
- The findings suggest that surgical ILM peeling prior to AAV vector delivery would be beneficial for retinal disease treatment and safe for effective transduction of the nonhuman primate retina.
Learn more about the adeno-associated virus (AAV) with the help of the given link:
brainly.com/question/28205495
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1. a. <span>is a possible explanation for events using prior knowledge
An inference </span><span>is a possible explanation for events using prior knowledge, therefore, inference is an educated guess which can provide a logical reasoning to an object, phenomenon or circumstance.
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<span><span>2. d. the amount of time ...
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</span>Since the amount of time can't clearly be controlled but only observed the other factors which is water, soil and type of plant can be manipulated in the study.
Hey there,
The answer is - aneurysm<span>
Hope this helps :))
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Answer:
PCR=Polymerase chain reaction
Explanation:
