Answer:
By preventing the synthesis of DNA halting cell growth.
Explanation:
Fluorouracil and methotraxate prevent the synthesis of the neucleoside Thymidine thus preventing DNA replication and elongation. Methotraxate has a structure analogous to Folic acid which is important for thymidine synthesis. Thus, it acts as a competitive inhibitor on dihdrofolate reductase an enzyme that is essential for tetrahydrofolate formation, a folic acid derivative.
Fluorouracil acts by inhibiting thymidylate synthase which catalyses an essential step in Thymidine synthesis.
False because extrusive rocks have fine-grained texture due to the rapid cooling of magna above the earth surface. On the other hand extrusive rocks have course grained texture due to slow cooling of magna beneath the Earth's surface
Coal is the most abundant global nonrenewable resource
