I think the answer is food
This line implies that humans, have been created in a sort of synthetic environment. Humans in this case, are now the most intellegent beings on the known universe, they have been monitored, similar to test subjects. These people/ this race, is more intelligent than man, and humans have been in an experiment this whole time.
Hope this helps.
Answer: I believe it was Dell Duke, because when you search all those peeps names Dell is the only one that works with Willow.
The answer to this is All of the above