Answer:
d. all endothelial cells would be venous
Explanation:
The Notch signaling pathway is a cell signaling system which consist basically of 4 NOTCH genes ( NOTCH1, NOTCH2, NOTCH3, and NOTCH4) each of them having the information to build a particular cell membrane receptor protein.
It has been demonstrated in zebrafish embryos that Notch signaling are highly determinant factors during vascular development, and a key function of these genes was specifically to regulate the differentiation of arterial fate in endothelial cells.
Notch signaling-deficient embryos showed a loss of expression of arterial markers such as ephrinB2 from arterial vessels with an accompanying expansion of venous markers into normally arterial domains. In contrast, embryos in which Notch signaling had been ectopically activated, meaning an activation out of "proper" place (where not expected, e.g. venous endothelial), exhibited the contrary phenotype, this is a suppression of vein-specific markers with ectopic expression of arterial markers in venous vessels.
To summarize, when Notch is supressed (in this case inhibited with a specific Notch inhibitor) arterial fate of endothelium is not followed, and venous fate is stablished. Thus, endothelial cells (those expected to form venous tissues but also arterial ones) would specified as venous.
Answer:
The Golgi complex is compromised
Explanation:
The Golgi complex helps in the process of synthesis and packaging of proteins and lipids, especially those proteins that are for exportation. The organelle´s function is to manage the recently synthesized proteins, to transform them, and to export them to other places.
Different proteins are synthesized in the endoplasmic reticulum and sent to the Golgi complex in vesicles, where it happens the final association of carbohydrates with proteins. Finally, protein is transported from the Golgi complex to its final destiny. Proteins destined to a certain place are packaged all together in the same vesicle and sent to the target organ. In the case of membrane proteins, they are packaged in vesicles and sent to the cell membrane where they get incrusted.
By being affected by the achondrogenesis 1a, the Golgi complex loses its functions and is incapable of finishing the protein synthesis and transport process, affecting other cells and their functions.
This type of water transition or change in phase of matter is known as FREEZING.
Water has molecules that are free flowing and have the ability to collide and bounce against each other, that's why it has that kind of characteristic that it takes the shape of its container.
When these molecules are exposed to lower or colder temperatures, the molecules tend to vibrate and get attracted towards each other, creating a semi-solid or completely solid material. In this example, liquid turned into frost because of the low temperature present within the environment.
Answer: D . maintain satisfactory academic progress
Explanation:
