Question

Two forms of hemophilia are determined by genes on the x chromosome in humans assume that a phenotypically normal woman whose father had hemophilia is married to normal and what is the probability that their first daughter will have hemophilia?

Answer 1

Answer:

The probability that this woman's daughter has hemophilia is 0%.

Explanation:

Haemophilia is a severe and most often hereditary coagulation disorder in which the individual's blood does not coagulate properly and can lead to uncontrolled bleeding that can be caused even spontaneously or by minor trauma.

Haemophilia is a resessive X-linked disease, so we can conclude that the woman exposed in the question has the hemophilia gene, but has normal coagulation. This is because this woman's father has hemophilia and donated the resurrective X chromosome to her, but the disease was prevented from manifesting because this woman, received from the mother the dominant comosso X, which prevented the disease from manifesting.   Based on this reasoning, if this woman marries a man who does not have hemophilia, the chances of her first daughter having the disease are 0%. Because this girl's father doesn't have hemophilia so the X chromosome he will give the girl is free of the gene for this disease, even if the girl gets her mother's X chromosome and that chromosome has the gene that codes for hemophilia, the girl won't manifest the disease.