The people who have high self esteem
I believe your answer is d. Derek is hungry or needs to have his diaper changed.
Option c could be correct but option d seems more likely
I hope this is the answer you're looking for and good luck.
Before modern medicine, in which treatment's with certain ethical therapies and medication, most patients with mental illness where placed in institutions no matter how severe, and were forced to go through unethical therapies such as electroshock or lobotomies.