OBJECTIVES: To analyze the occurrence and types of neoplasias that have developed in patients submitted to orthotopic heart transplantation in the Cardiac Transplantation Program of the Paulista School of Medicine, Federal University of São Paulo.
METHODS: The present study presents an observational analysis of 106 patients submitted to orthotopic heart transplantation from November 1986 to September 2002, who survived for more than 30 days after the procedure. The immunosuppressive regimen consisted of triple therapy with cyclosporin A, azathioprine and corticosteroid. Only two patients received, in addition to triple therapy, the addition of orthoclone OKT-3. The mean follow-up period was 61.4 months. (variation from two months to 192 months).
RESULTS: Twenty-three patients (21.3%) developed neoplasias, of which 56.5% had skin neoplasms, 30.1% had solid tumors and 13.4% had post-transplantation lymphoproliferative disease (PTLD). The mean interval between transplantation and the diagnosis of neoplasia was: skin - 54.9 months, solid tumors - 24.8 months and DLPT - 70.3 months.
CONCLUSIONS: The occurrence of malignant neoplasms was relatively common in the analyzed population. Skin cancer prevailed in relation to other neoplasms and solid tumors were more diagnosed than lymphoproliferative diseases in this series of patients.
The answer is Personification
Answer:
cause
Explanation:
i am princes of nature of queen arigato gosaimas
As per assembling a writing plan for an essay, the better answer, if not the best, would be B. Material that catches the reader's interest.
Many would argue that the correct answer would be D. the general idea of your essay or maybe C. a brief summary of your conclusion or perhaps A. the first section of the body of your essay. Well, they are all correct. As long as what follows is duly taken noted and is consistent to keep the flow of the essay that when the final paper is read, it isn't confusing in any way. Though generally speaking, what should come first would be the material that catches the reader's interest.
The reader is introduced to the marlin because Santiago sees one of the projecting sticks dip in the water (B).
In <em>The Old Man and the Sea</em>, the main character becomes aware of the presence of the marlin when he realizes something is tugging at his hundred-fathom-deep fishing line. Because of the strength of the bite, the stick to which the line is attached is pulled into the water. Santiago immediately recognizes the fish as being a large marlin.
