Answer:
The term "Something The Lord Made" was said by Alfred Blalock to Vivien Thomas and was referring to a medical procedure that Vivien preformed that was so perfect it was described as something the lord made.
The epidermis layer was broke also known as skin which protects infectious bacteria and viruses from entering.
It would cause Cardiogenic Shock. A more percise diagnosis for this though would be Cardiac Tamponade. Hope this helps :)