After 12 hours without eating, Seth is very hungry. It is likely that Seth's blood glucose level is LOW and his blood insulin level is HIGH.
A situation in which the blood glucose level is low is called hypoglycemia. In this situation, the level of glucose in the blood is much more lower than the normal level. This may be caused by a lot of factors. When the blood glucose level is low, the glucagon hormone mobilize the liver to release glycogen which is converted to glucose. The presence of glucose in the blood increase the level of insulin secretion which in turn increased the feeling of hunger in the individual. 
        
             
        
        
        
Answer:
what is the question I will help you I'm comments 
 
        
             
        
        
        
Explanation:
Adaptations generally occur in order to increase the fitness and thus survival of organisms. By being able to adapt to the changing environment, organisms are better able to survive and reproduce. ... Many people are under the impression that species require thousands or even millions of years to adapt.
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hi <3
changes in the enzyme's shape would decrease its ability to function as this would change the active site of the enzyme, meaning it is harder for it to carry out its job. 
this is why we try to keep enzymes in their optimum environmental conditions so they can function their best
hope this helps :)