Answer:
Mesopotamia is located in the region now known as the Middle East, which includes parts of southwest Asia and lands around the eastern Mediterranean Sea Situated in the fertile valleys between the Tigris and Euphrates rivers, the region is now home to modern day iraq Kuwait Turkey and Syria
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It would be difficult for the United States for two reasons, the fact that none of the land was mapped other than the areas that previous voyagers had gone through, and the natural landscape of the area, and last, Native American Hostility.
Three examples: When pioneers would voyage to the west, there would often be encounters were they would be attacked by animals that had not been seen before, bears, sneaks, different wolves, and many more. They barely knew the natural resources of the area, such as food, etc.
The next example, no mapping, would be difficult because for the most part, they had no sense of navigation except for the few maps that had been made, even then, would be difficult to navigate.
Native Americans did not appreciate the pioneers coming into the land they considered their own, they resembled hostility and would even kill the civilians that would travel through the land, or capture them.
Hope this helps!! <3
I believe it is equality. I am not sure in what context this is asking, but I am pretty sure it is equality.