Answer and Explanation:
Ergotamine has been used for over 50 years and was the first specific drug to treat migraine attacks. Its therapeutic effect is due in part to its ability to contract the vessels. It is a vasoconstricting alkaloid used in migraine attacks, when treatment with non-steroidal anti-inflammatory drugs has no effect.
The mechanism of action of ergotamine is complex. The molecule has structural similarities to neurotransmitters such as seratonin, dopamine and adrenaline, and can therefore bind to various receptors and function as an inhibitor. Its use in the treatment of migraines is due to its vasoconstrictor effect of extracerebral intracranial blood vessels through their binding to the 5-HT1B receptor and inhibition of neurotransmitter binding.
Overuse of ergotamine may cause nausea, vomiting (to direct effects on the Central Nervous System in the vomiting centers) , malaise, headache, constriction of peripheral vessels and more severe effects such as ischemia of the extremities.
Ergotamine poisoning is called ergotism.
Ergotamine should not be used in patients with peripheral arterial or venous vascular insufficiency, ischemic heart disease, cerebrovascular disease, systemic infection and hypertension without effective control.
Explanation:
Acquired immune deficiency syndrome, orAIDS, is an autoimmune disease that is the final stage of human immunodeficiency virus, or HIV, which attacks the immune system similar to other autoimmune diseases and leaves the body susceptible to other diseasesand infections.
Answer:
implicit memory
Explanation:
Implicit memory, also called nonassociative memory, is memory that evokes skills, word cues, objects, associations, non-association-based learning, and mechanical learning. Learning to drive or ride a bicycle is a good example of using this memory. Although damage to the hypothalamus causes memory-related problems, implicit memory is not impaired by such damage, so the client is able to learn and memorize new activities.
