A comma should be after each separate things you are listing. The answer is:
<span>
The
Library of Congress is home to the world's most extensive comic-book
collection, oldest original newspaper collection, and most abundant
collection of cartographic items.</span>
Because on Black Friday there are crazy people who can hurt you and you might not find anything because of what time you go in the day
Run-on sentences make text more difficult to read.
Run-on sentences can change the intended meaning of a text.
Run-on sentences can make a sentence confusing.
Overall, run-on sentences are just a bad idea.
Kafka uses peculiar and round-about ways of saying things when talking about Gregor in order to convey the complications that Gregor's personality presents. Gregor is a man who is completely controlled by the expectations that society and his family have of him. He knows that he should work hard, be responsible, sacrifice everything for his family and be the breadwinner. These are the expectations that dominate his whole life. The reason why he is so overwhelmed by them is because these stem from his social context, and not from his personal goals or dreams.
Kafka choice of language in this passage reflects this feeling. Gregor is constantly doing what he <em>ought</em> to do, and not what he <em>wants</em> to do or what he believes in. Even when going through extremely frightening and confusing situations, he remembers that what he ought to do is remain calm. And he strives to satisfy this expectation, regardless of what his true feelings might be.
