ADP, NAD+, CoA-SH, and pyruvate are the molecules that inhibit the pyruvate dehydrogenase complex.
<h3>What is pyruvate dehydrogenase complex?</h3>
PDC3 triggers the oxidative decarboxylation of pyruvate, resulting in the creation of acetyl-CoA, CO2, and NADH.
The PDC plays a crucial role in the oxidation of glucose by connecting the glycolytic pathway to the tricarboxylic acid cycle's oxidative pathway.
ADP, NAD+, CoA-SH, and pyruvate all inhibit it. PDK prevents glycolysis from being coupled to GO by inhibiting its target enzyme PDH.
Thus, the answer is ADP, NAD+, CoA-SH, and pyruvate .
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