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B. toxoplasmosis gondii can be caused by cat litter
If a child can’t rely on his carers to look after him and respond consistently, this has been noted to have potentially very serious and damaging consequences for the adult that child will become. If adults are seriously inconsistent or unresponsive in their behaviour to the child, he may become very anxious as he is not able to predict how the adults around him will act; the child may even give up trying to get his needs met.Children whose caregivers respond sensitively to the child’s needs at times of distress and fear in infancy and early childhood develop secure attachments to their primary caregivers. These children can also use their caregivers as a secure base from which to explore their environment. They have better outcomes than non-securely attached children in social and emotional development, educational achievement and mental health. Early attachment relations are thought to be crucial for later social relationships and for the development of capacities for emotional and stress regulation, self-control and metallisation…
The problems the girl exhibits when eating fruit is most likely due to elevated levels of fructose-1-phosphate in liver cells
Define Hereditary fructose intolerance (HFI).
Fruit sugar fructose and its precursors cannot be digested in people with hereditary fructose intolerance (HFI). The accumulation of fructose-1-phosphate in the liver, kidney, and small intestine is caused by a lack of activity of the enzyme fructose-1-phosphate aldolase.
The patient has HFI, which is due to a mutation in aldolase B. Sucrose would still be cleaved by sucrase, thus it would not increase in the stool. Fructose would not be metabolized normally, therefore it would be elevated in the blood and urine. Aldolase B would not cleave fructose 1-phosphate, thus its levels would be elevated and the product, glyceraldehyde, would not be produced.
HFI patients frequently grow to dislike fruit and sweets intensely. After consuming fructose-containing foods, they may experience symptoms like excruciating stomach pain, vomiting, and low blood sugar.
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