Monoclonal antibodies (mAbs) are produced by introducing an antigen to a mouse and then fusing polyclonal B cells from the mouse's spleen to myeloma cells. The resulting hybridoma cells are cultured and continue to produce antibodies to the antigen.
Explanation:
An example of a monoclonal antibody is blinatumomab (Blincyto, Amgen), used to treat certain cancer, types of acute lymphocytic leukemia.
