Autoantibodies that contribute to the destruction of beta cells contributes to the development of type I diabetes mellitus (DM)
Explanation:
The autoantibodies produced in the cells of the islet of Langerhans in the pancreas are the main contributors of type I diabetes mellitus, which is an autoimmune-mediated disease.
DM type I is caused due to inhibition of insulin secretion by the beta cells of the pancreas. The autoantibodies are produced due to the presence of autoantigens like GAD65 which causes autoimmune pathogenesis of the pancreatic beta cells.
Along with these autoantibodies, the T-cell receptors act as mediators in the destruction of beta cells which finally results in DM.
If you are reading this guide, you’ve probably already had a Pap test and may have been told by your health care provider (HCP) that your Pap test results were abnormal. Maybe you’re worried and wondering what this means and how it will affect you. However, knowing the possible reasons for abnormal results will help.
What is a Pap test?
A Pap test, also called a “Pap smear,” is part of a pelvic exam. The word “Pap” is short for Papanicolaou, which is the last name of the doctor who studied changes in cervical cells. A Pap test is usually done at age 21 unless you have special risks such as immune problems or HIV. It’s the only way to check the cells on your cervix for changes that can lead to cancer. Your HCP usually checks for STIs (sexually transmitted infections) such as chlamydia and gonorrhea at the same time.
How is a Pap test done?
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The emotional changes cause they might affect you
