Answer:
Water based fluid
Explanation:
The internal environment consists of water based fluid in which the cells of the body present. A fluid called interstitial fluid or tissue fluid bathes the cells and provides essential nutrients to the cell. The human skin has fatty layers that helps to maintain internal heat which is produced by the body when the outside environment is cold. When there is cold in the environment, people lives in warm shelters and wear warm clothes in order reduce the impact of cold environment.
<span>he Streptococcus pneumoniae capsule is vital for virulence and may inhibit complement activity and phagocytosis. However, there are only limited data on the mechanisms by which the capsule affects complement and the consequences for S. pneumoniae interactions with phagocytes. Using unencapsulated serotype 2 and 4 S. pneumoniae mutants, we have confirmed that the capsule has several effects on complement activity. The capsule impaired bacterial opsonization with C3b/iC3b by both the alternative and classical complement pathways and also inhibited conversion of C3b bound to the bacterial surface to iC3b. There was increased binding of the classical pathway mediators immunoglobulin G (IgG) and C-reactive protein (CRP) to unencapsulated S. pneumoniae, indicating that the capsule could inhibit classical pathway complement activity by masking antibody recognition of subcapsular antigens, as well as by inhibiting CRP binding. Cleavage of serum IgG by the enzyme IdeS reduced C3b/iC3b deposition on all of the strains, but there were still marked increases in C3b/iC3b deposition on unencapsulated TIGR4 and D39 strains compared to encapsulated strains, suggesting that the capsule inhibits both IgG-mediated and IgG-independent complement activity against S. pneumoniae. Unencapsulated strains were more susceptible to neutrophil phagocytosis after incubation in normal serum, normal serum treated with IdeS, complement-deficient serum, and complement-deficient serum treated with IdeS or in buffer alone, suggesting that the capsule inhibits phagocytosis mediated by FcÎł receptors, complement receptors, and nonopsonic receptors. Overall, these data show that the S. pneumoniae capsule affects multiple aspects of complement- and neutrophil-mediated immunity, resulting in a profound inhibition of opsonophagocytosis.</span>
A fish with gills,
A leopard with spots
A bird with its feathers
To help work place with the system
Answer:
The neutrophil is the first line of defense, it is called as PMN OR POLYMORPHONUCLEAR NEUTROPHIL, this cell is said to be the first line of defense for the first to reach the area of infection or in the area of trauma, this upon reaching that area (where it is attracted by defense chemomodulators) it recognizes the bacteria or the foreign body as an antigen, since these do not present the cellular histocompatibility complex of our organism, by recognizing it as an antigen, this cell can detect that it is not something typical of our body but something new that was inoculated, is how this phagocyte to the bacteria and induces its own programmed cell death.
In an injury or infection, the purulent collection is not only debris and pathogenic microorganisms, but they are dead cell bodies of PMNs that induce their own cell death with the battery inside to be able to inhibit its advance in our body, when this phenomenon passes the PMN it is called a peach.
Explanation:
In the event that no antibodies are present, it would not change much if it is the first time that the bacteria enters our body since the formation of antibodies by the lymphocyte cell line occurs as the last stage of immunity (neutrophils appear first, then the antigen presenting cells and finally the lymphocyte lineage in charge of making immunological memory with antibodies).
The PMN are guided more than anything by the humoral factor of the immune response, but the proinflammatory factor like cytokines or leukins, but not by the antibodies, that is why he wrote this process of bacterial assimilation in the response.
