Cardinal motor features of Parkinson's disease (PD) include bradykinesia, rest tremor, and rigidity, which appear in the early stages of the disease and largely depend on dopaminergic nigrostriatal denervation. Intermediate and advanced PD stages are characterized by motor fluctuations and dyskinesia, which depend on complex mechanisms secondary to severe nigrostriatal loss and to the problems related to oral levodopa absorption, and motor and nonmotor symptoms and signs that are secondary to marked dopaminergic loss and multisystem neurodegeneration with damage to nondopaminergic pathways. Nondopaminergic dysfunction results in motor problems, including posture, balance and gait disturbances, and fatigue, and nonmotor problems, encompassing depression, apathy, cognitive impairment, sleep disturbances, pain, and autonomic dysfunction. There are a number of symptomatic drugs for PD motor signs, but the pharmacological resources for nonmotor signs and symptoms are limited, and rehabilitation may contribute to their treatment. The present review will focus on classical notions and recent insights into the neuropathology, neuropharmacology, and neurophysiology of motor dysfunction of PD.
What a persons mental and emotional health can be directly affected by anything really but mostly happiness
Answer:
true
Explanation:
Some people, like me, are empaths, that means that we are able to easily sense other peoples emotions and feelings. Others arent able to do that, and even after being given multiple hints, they still wont understand. So, my suggestion, is that if you are having trouble with your emotions, or your needs, you should talk to someone who you trust and who can help you.
Answer:
women bexause...
Explanation:
Throughout history, the central role of women in society has ensured the stability, progress and long-term development of nations. Globally, women comprise 43 percent of the world’s agricultural labor force – rising to 70 percent in some countries. For instance, across Africa, 80 percent of the agricultural production comes from small farmers, most of whom are rural women. It’s widely accepted that agriculture can be the engine of growth and poverty reduction in developing nations. Women, notably mothers, play the largest role in decision-making about family meal planning and diet. And, women self-report more often their initiative in preserving child health and nutrition.
