when working out you want to make sure you can meet the task at hand. go little by little until you are able to meet your goal. so to start i would rule out D.
The factors that can affect the amount of urine excreted everyday include the following:
1. Blood glucose level. Also known as hyperglycemia, high levels of sugar in the blood will trigger frequent urination.
2. Blood pressure. The kidneys act to regulate blood pressure in the body by increasing or decreasing the amount of urine produced.
3. Salt. A high salt diet causes fluid retention and subsequently increased urination.
4. Alcohol. Alcohol consumption reduces production of the hormone vasopressin responsible for re-absorption of water back into the blood stream. When this hormone is not being produced as normal, fluids freely fill up the bladder leading to frequent urination.
5. Exercise (sweating)
6. Temperature of the environment
7. Level of fluid intake.
FOR EXAMPLE:
Let's say you've been taking melatonin every single night to help you sleep. After a while, you may notice that it begins to take more and more melatonin for it to work like it did the first night you took it. You were taking one per night, but you end up taking 3 per night to get the same effect because your body has resistant to the drug.
ANSWER:
After a while of taking antibiotics, microorganisms in your body may become resistant to the antibiotics (which is potentially dangerous). This occurs when bacteria change to reduce the effects of a drug.
It only takes a few seconds to kick in.