When insulin is deficient , GLUT4 transporters are not inserted into the cell membranes , glucose is not transported into the cells and the blood glucose concentration increases.
Insulin deficiency provides more amino acid and glycerol substrates for glucose synthesis ie increased gluconeogenesis .
With a deficiency of insulin, there is both increased hepatic glucose production through increased glycogenolysis and gluconeogenesis as well as decreased glucose use. The result is hyperglycemia.
To know more about insulin deficiency here
brainly.com/question/12978381
#SPJ4
1. The correct answer is option A
The thickest layer is Dermis which is made up of two layers papillary and reticular. The reticular dermis is the lower layer of the dermis and is made up of dense irregular connective tissue featuring collagen fibers.
2. The correct answer is option E
Bone is composed of fibrous and mineralized connective tissues which is enriched in collagen and calcium phosphate.
3. The correct answer is option C
Muscles are composed of two major protein filaments: a thick filament composed of the protein myosin and a thin filament composed of the protein actin. These two filaments slide over each other to repetitively contract the muscles.
