The function of a protein is determined by its shape. The shape of a protein is determined by its primary structure (sequence of amino acids). The sequence of amino acids in a protein is determined by the sequence of nucleotides in the gene (DNA) encoding it.
It is probably the l<span>amellae.
The lamellae are sheets of bony matrix. This bony matrix is produced by o</span>steoblasts, which are cells that synthesise collagen<span> and specialised proteins like </span>osteocalcin<span> and </span>osteopontin. These are then the most important constituents of the bony matrix.
the answer is the first one: by producing random changes in an organism's genetic code
