Answer:
mutations cause most cases of cancer. Some acquired mutations can be caused by things that we are exposed to in our environment, including cigarette smoke, radiation, hormones, and diet. Other mutations have no clear cause, and seem to occur randomly as the cells divide.
Temperature can cause an enzymes shape and function to alter due to the fact that once an enzyme reaches its optimum level, if it goes over it begins to denature. If the temperature is below optimum, then an enzyme will work at a slower rate. Also, the pH can affect an enzyme.
Basically, the cell wouldn't be able to "breathe," as the mitochondria is where the respiratory functions of the cell happens. No energy would be produced, and then the cell would stop moving and die.
