Question

Even after taking into account all of the variants discovered by this study, there are still likely to be other variants that you have not discovered. The affected and unaffected cohorts are roughly the same size and are drawn from a similar population with similar ancestry. All of the following modifications to the study are likely to allow identification of new variants associated with the disease, EXCEPT ____________.

Answer 1

Question Completion with Options:

a. increasing the size of your cohorts.

b. increasing the diversity of your cohorts.

c. increasing the size of your affected cohort.

d. increasing the diversity of your affected cohort.

Answer:

All of the following modifications to the study are likely to allow identification of new variants associated with the disease, EXCEPT

a. increasing the size of your cohorts.

Explanation:

Option A is chosen because increasing the size of the cohorts will be equally divided between the affected and unaffected cohorts since the study discovered that these two classes are roughly the same size.  Therefore, new variants of the disease may not likely be identified and isolated unless the other modification options are followed instead of Option A.