It is called THERAPEUTIC INDEX. Therapeutic index is the comparison of the amount of a particular drug that causes the desired therapeutic effects and the amount that causes toxicity. The index can be low or high. A drug with a low therapeutic index will require only a small increase in dose to produce toxic effects in users.
<h2>CRISPR/Cas9</h2>
Explanation:
CRISPR can be used to reintroduce dystrophin back into the KO mouse
- CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats and is used to for gene editing
- CRISPR/Cas-mediated genome editing has been shown to permanently correct DMD mutations and restore dystrophin function in mouse models
- Germline editing by injecting zygotes with CRISPR/Cas9 editing component was first done in mdx mice by correcting the mutated exon 23
- Postnatal editing of mdx mice was then achieved using recombinant adeno-associated virus to deliver CRISPR/Cas9 genome editing components and correct the dystrophin gene by skipping or deleting the mutated exon 23 in vivo
- Germline and postnatal CRISPR/Cas9 editing approaches both successfully restored dystrophin function in the mice and same technique can be used for KO mouse model
Answer:
"GFP contained in synaptic vesicles moved into the synaptic cleft by exocytosis."
Explanation:
Synaptic vesicles are small membrane sacs that carry neurotransmitters from the cell body where they are produced, to the presynaptic membrane of the terminal button where they are released. The release zone of the presynaptic membrane contains voltage-dependent calcium channels. When an action potential depolarizes the presynaptic plasma membrane, 
-channels open, and flows into the nerve terminal to trigger the exocytosis of synaptic vesicles, thereby releasing their neurotransmitters into the synaptic cleft
Answer:
Hydrogen
Explanation:
2 between A-T and 3 between G-C
Answer:
Translation
Explanation:
When assembled in the nucleus, mRNA peels off and moves to the cytoplasm. Here, it attaches to a ribosome. As the mRNA moves along the ribosome its information is translated into the appropriate amino acids which are assembled into a polypeptide.
